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MUO plays important role in discovery of lung-cancer gene

Lung cancer is the leading cause of cancer death in the United States for both men and women. The Medical University of Ohio is inviting families to take part in an important genetic research project.

The genetic research project, entitled "Genetic Epidemiology of Lung Cancer: Gene Identification in High Risk Families," in an effort to discover one or more genes responsible for human lung cancer.

Between 5 and 10% of lung cancer cases are inherited, or passed down through the same side of the family tree. Clues that suggest lung cancer is inherited include: multiple family members on the same side of the family tree affected with lung cancer, lung cancer at an early age, lung cancer in non-smokers, and the presence of smoking related cancers in the family tree, such as throat, tongue, bladder, or pancreatic cancers.

If we discover a gene(s) responsible for lung cancer, it could lead to tests that may help screen for lung cancer in a family with a history of lung cancer. This could improve the detection, treatment, and prevention of lung cancer in the future.

Funding for this project is from the National Institute of Health and is a joint effort with seven other centers from across the United States.