| Research Home | Basic Neuroscience Research |
| Clinical Research | Grant Funded Research |
| Source (Agency) | Title | PI | Period of Support |
| Teva Pharma | Sub-study to evaluate the effect of an oral dose of tyramine in subjects completing 26 weeks of participation in PRESTO (A multicenter, double blind, randomized, placebo controlled, parallel group study for the efficacy, tolerability and safety of rasagiline mesylate in levodopa treated Parkinson’s disease patients with motor fluctuations | G.E. Tietjen | 07/01 - 06/03 |
| Yamanouchi, Inc. | Effects of YM872 on the evolution of lesion volume as measured by diffusion weighted imaging in patients with acute ischemic stroke | G.E. Tietjen | 01/01 - 01/03 |
| Yamanouchi, Inc. | A multicenter, randomized, double blind, placebo controlled, study to evaluate neurologic function and disability in patients with acute ischemic stroke given tissue plasminogen activator plus YM872 or tissue plasminogen activator plus placebo | G.E. Tietjen | 01/01 - 01/03 |
| NIH | African-American Antiplatelet Stroke Prevention Study |
G.E. Tietjen | Ongoing |
| NIH | Warfarin vs Aspirin for Symptomatic Intracranial Disease | G.E. Tietjen | Ongoing |
| Parke-Davis | A double blind, randomized placebo controlled study of Atorvastatin as prevention of cerebral vascular events in patients with a previous transient ischemic attack (TIA) or stroke (Lipitor) | G.E. Tietjen | Ongoing |
| NIH | College of NursingIA (Stroke Outcome and Inebriating of Intracranial Atherosclerosis) | G.E. Tietjen | 07/01 - 06/03 |
| Glaxo Wellcome | A randomized, open label, double blind, parallel group, placebo controlled study to evaluate the efficacy of oral naratriptan (Amerge 2.5 mg) when used in combination with rectal prochlorperazine (Compazine 25 mg) for the treatment of migraine headaches | G.E. Tietjen | Ongoing |
| AHA/Merck | Cerebral blood flow in female migraineurs with livedo reticularis | G.E. Tietjen | 03/01 - 03/03 |
| Charles A. Dana Foundation | Migraine as a risk factor for stroke: role of cytokine activation | G.E. Tietjen | 01/01 - 01/04 |
| American Headache Society | The interaction of migraine and low estrogen content oral contraceptive use upon hemostasis | G.E. Tietjen | 07/01 - 06/03 |
| American Headache Society |
American Headache Society Woman’s Headache Diary Study | G.E. Tietjen | 05/01 - 06/03 |
| Source (Agency) | Title | PI | Period of Support |
| MUO Cancer Institute |
p38-mediated Signal Transduction In Glial Cells |
Linda Dokas | 7/1/00-6/30/03 |
| AFAR-Ohio Affiliate |
Receptor-mediated APP Secretion and Presynaptic Function |
Linda Dokas | 1/1/01-12/31/01 |
| NIH | Synaptic Mechanisms of Hippocampal Benzodiazepine Tolerance | Elizabeth Tietz; Linda Dokas, co-investigator (10% effort) |
4/1/00-3/30/05 |
| NIH | Biochemistry of Vestibular Compensation |
Donald Godfrey; Linda Dokas, co-investigator (2% effort) |
7/1/98-6/30/03 |
| Source (Agency) | Title | PI | Period of Support |
| Schwarz-Pharma | A Multicenter, Multinational, Phase III, Randomized, Double-blind, Placebo Controlled Trial of the Efficacy and Safety of the Rotigotine CDS Patch (2 target doses) in Subjects with Advanced Stage, Idiopathic Parkinson’s Disease Who Are Not Well Controlled on Levodopa | L. Elmer, MD, PhD | 12/01 - 5/03 |
| Schwarz-Pharma | A Multicenter, Multinational, Phase III, Randomized, Double-blind, Placebo Controlled Trial of the Efficacy and Safety of the Rotigotine CDS Patch in Subjects with Early Stage, Idiopathic Parkinson’s Disease. | L. Elmer, MD, PhD | 12/01 - 5/03 |
| Source (Agency) | Title | PI | Period of Support |
| Mylan Pharmaceuticals | Subcutaneous Apomorphine in patients with advanced Parkinson’s disease | Larry Elmer, M.D., Ph.D. | 01/01 - 01/03 |
| Parkinson’s Study Group and TEVA Pharma. | Multicenter, Randomized, Double-Blind, Parallel Group Study Comparing TV-1203/Carbidopa Dispersible Tablets with Levodopa/ Carbidopa (LD/CD) Tablets in Patients with Response Fluctuations (includes extension phase) | L. Elmer, M.D., Ph.D. | 2001-2003 |
| Parkinson’s Study Group and TEVA Pharma. | A Multicenter, US and Canada, Randomized, Double-Blind, Parallel Group Study for the Efficacy, Tolerability, and Safety of Rasagiline Mesylate in Levodopa Treated Parkinson’s Disease (PDP Patients with Motor Fluctuation (includes an extension phase) | L. Elmer, M.D., Ph.D. | 2001-2003 |
| Parkinson Study Group, Indiana Univ and NIH | Parkinson’s Research: The Organized Genetics Initiative | L. Elmer, M.D., Ph.D. | 1998-2003 |
| Source (Agency) | Title | PI | Period of Support |
| Myoclonus Research Foundation | Post Hypoxic changes in GABAA receptor function and subunit expression in human NT2N Neurons in vitro | Greenfield | 8/1, 2003 - 6/30, 2003 |
| American Academy of Neurology | Effects of Phosphorylation on GABAA receptors | Greenfield | No cost extension through 6/30/03 |
| Source (Agency) | Title | PI | Period of Support |
| Allergan Pharmaceutical | Evaluating the use of Botulinum Toxin for Pain Control in Fibromyalgia | Noor Pirzada |
| Source (Agency) | Title | PI | Period of Support |
| Abbott | Intravenous Valproate in the Treatment of Non-Convulsive Status Epilepticus | Imran Ali, M.D. | 01/05/01-01/04/03 |
| Glaxo Wellcome | A Multi Center, Double-Blind, Randomized, Placebo-Controlled, Parallel-Group Evaluation of Lamotrigine Adjunctive Therapy in Subjects with Primary Generalized Tonic Clonic Seizures | Imran Ali, M.D. | 03/01/01 - 01/31/03 |